GPR177/WLS antibody (Middle Region)

Catalog No. ABIN2781860

This Rabbit Polyclonal antibody specifically detects GPR177/WLS in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for GPR177/WLS antibody (Middle Region) (ABIN2781860)

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR177/WLS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPR177/WLS Antibody

Binding Specificity: Middle Region

Purpose: GPR177 Antibody - middle region

Sequence: DIRLVGIHQN GGFTKVWFAM KTFLTPSIFI IMVWYWRRIT MMSRPPVLLE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GPR177. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GPR177

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44432-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR177/WLS

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Alternative Name: GPR177

Background:

Background Information: GPR177 has signal transducer activity. It is positive regulation of I-kappaB kinase/NF-kappaB cascade.

Gene Name: Wntless homolog (Drosophila)

Alternative Symbols: EVI, MRP, GPR177, mig-14, C1orf139

Protein Name: Protein wntless homolog

Molecular Weight: 62kDa

Gene ID: 79971

NCBI Accession: NP_001002292

UniProt: Q5T9L3

Pathways: WNT Signaling