DPP10 antibody (Middle Region)

Catalog No. ABIN2781884

The Rabbit Polyclonal anti-DPP10 antibody is suitable to detect DPP10 in samples from Human, Mouse, Rat, Horse, Cow, Rabbit, Dog and Guinea Pig. It has been validated for WB.

Quick Overview for DPP10 antibody (Middle Region) (ABIN2781884)

Target: DPP10 (Dipeptidylpeptidase 10 (DPP10))

Reactivity: Human, Mouse, Rat, Horse, Cow, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPP10 Antibody

Binding Specificity: Middle Region

Purpose: DPP10 Antibody - middle region

Sequence: VNYTMQVYPD EGHNVSEKSK YHLYSTILKF FSDCLKEEIS VLPQEPEEDE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DPP10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPP10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44474-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPP10

Target: DPP10 (Dipeptidylpeptidase 10 (DPP10))

Alternative Name: DPP10

Background:

Background Information: DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma.This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Dipeptidyl-peptidase 10 (non-functional)

Alternative Symbols: DPL2, DPPY, DPRP3, DPRP-3

Protein Name: DPPY splice variant d EMBL ABI16087.1

Molecular Weight: 90kDa

Gene ID: 57628

NCBI Accession: NP_001004360

UniProt: Q0GLB7