AGPAT2 antibody (C-Term)

Catalog No. ABIN2781950

This Rabbit Polyclonal antibody specifically detects AGPAT2 in WB and IHC. It exhibits reactivity toward Human, Cow, Dog, Horse and Saccharomyces cerevisiae.

Quick Overview for AGPAT2 antibody (C-Term) (ABIN2781950)

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Reactivity: Human, Cow, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGPAT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AGPAT2 Antibody

Binding Specificity: C-Term

Purpose: AGPAT2 Antibody - C-terminal region

Sequence: QVPIVPVVYS SFSSFYNTKK KFFTSGTVTV QVLEAIPTSG LTAADVPALV

Predicted Reactivity: Cow: 85%, Dog: 92%, Horse: 77%, Human: 100%, Yeast: 91%

Characteristics: This is a rabbit polyclonal antibody against AGPAT2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44636-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AGPAT2

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Alternative Name: AGPAT2

Background:

Background Information: AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.

Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

Alternative Symbols: BSCL, BSCL1, LPAAB, 1-AGPAT2, LPAAT-beta

Protein Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta

Molecular Weight: 31kDa

Gene ID: 10555

NCBI Accession: NP_006403

UniProt: O15120