MPG antibody (Middle Region)

Catalog No. ABIN2781975

This anti-MPG antibody is a Rabbit Polyclonal antibody detecting MPG in WB. Suitable for Human, Rat, Cow, Dog and Horse.

Quick Overview for MPG antibody (Middle Region) (ABIN2781975)

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Reactivity: Human, Rat, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MPG Antibody

Binding Specificity: Middle Region

Sequence: QRDLAQDEAV WLERGPLEPS EPAVVAAARV GVGHAGEWAR KPLRFYVRGS

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MPG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MPG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 281 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MPG

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Alternative Name: MPG

Background: MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Alias Symbols: AAG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg, ADPG
Protein Interaction Partner: HSD17B14, RPA3, RPA2, RPA1, HECW2, UHRF2, LARP4, OBSCN, DHX33, PRPF38B, GNL2, UHRF1, RACGAP1, RRP7A, GNL3, NOC2L, TFIP11, RPRD2, CLASP2, RRP1B, KDM2A, MORF4L1, FXR2, SART1, KHSRP, SRSF1, RFC4, PPP1R10, EXOSC9, PKM, PRDX1, NCBP1, LHCGR, GSN, FLG, KPRP, TWI
Protein Size: 281

Molecular Weight: 31 kDa

Gene ID: 4350

NCBI Accession: NM_001015054, NP_001015054

UniProt: P29372

Pathways: DNA Damage Repair