FAM134B antibody (Middle Region)

Catalog No. ABIN2782025

Cited in 1 publication. The Rabbit Polyclonal anti-FAM134B antibody (ABIN2782025) specifically detects FAM134B in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae samples.

Quick Overview for FAM134B antibody (Middle Region) (ABIN2782025)

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM134B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM134B Antibody

Binding Specificity: Middle Region

Purpose: RETREG1 Antibody - middle region

Sequence: DFGIGEYINQ KKRERSEADK EKSHKDDSEL DFSALCPKIS LTVAAKELSV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against FAM134B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM134B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44826-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FAM134B antibody (ABIN2782025)

Tang, Chui, Fatima, Kok, Pak, Ou, Hui, Wong, Wong, Law, Tsao, Lam, Beh, Srivastava, Chan, Ho, Tang: "Oncogenic properties of a novel gene JK-1 located in chromosome 5p and its overexpression in human esophageal squamous cell carcinoma." in: International journal of molecular medicine, Vol. 19, Issue 6, pp. 915-23, (2007) (PubMed).

Target Details for FAM134B

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Alternative Name: RETREG1

Background:

Background Information: The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: reticulophagy regulator 1

Alternative Symbols: JK1, JK-1, FAM134B

Protein Name: reticulophagy regulator 1

Molecular Weight: 55kDa

Gene ID: 54463

NCBI Accession: NP_001030022

UniProt: Q9H6L5