Fukutin antibody (C-Term)

Catalog No. ABIN2782105

Product Details anti-Fukutin Antibody

Target: Fukutin (FKTN)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FGKVEDSLEL SFQGKDDVKL DVFFFYEETD HMWNGGTQAK TGKKFKYLFP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FKTN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human FKTN

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN (FKTN Products)

Synonyms: FCMD antibody, fcmd antibody, im:7163166 antibody, zgc:162828 antibody, FKTN antibody, CMD1X antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, D830030O17Rik antibody, Fcmd antibody, fukutin antibody, fukutin S homeolog antibody, Fukutin antibody, FKTN antibody, fktn antibody, fktn.S antibody, Bm1_09375 antibody, Bm1_09380 antibody, Bm1_44655 antibody, Fktn antibody

Background: The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: FCMD, CMD1X, LGMD2M, MDDGA4, MDDGB4, MDDGC4
Protein Size: 329

Molecular Weight: 36 kDa

Gene ID: 2218

NCBI Accession: NM_001079802, NP_001073270

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process