Integrin beta 5 antibody (Middle Region)

Catalog No. ABIN2782162

The Rabbit Polyclonal anti-Integrin beta 5 antibody has been validated for WB. It is suitable to detect Integrin beta 5 in samples from Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Guinea Pig and Sheep.

Quick Overview for Integrin beta 5 antibody (Middle Region) (ABIN2782162)

Target: Integrin beta 5 (ITGB5)

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 5 Antibody

Binding Specificity: Middle Region

Sequence: LFFTATCQDG VSYPGQRKCE GLKIGDTASF EVSLEARSCP SRHTEHVFAL

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ITGB5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ITGB5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 799 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Integrin beta 5

Target: Integrin beta 5 (ITGB5)

Alternative Name: ITGB5

Background: Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Alias Symbols: FLJ26658
Protein Interaction Partner: NOTCH2NL, KRTAP10-8, KRTAP10-9, KRT40, MTUS2, EHMT2, EPHA2, SNTA1, SRSF9, UBC, PDIA3, EWSR1, ALB, MYC, MERTK, PTK2, PPARD, ITGA3, TENC1, PALLD, ITGB3BP, CYR61, PAK4, ZBTB17, NUMB, DAB1, DOK1, FHL2, LTBP3, MYO10, DAB2, EPS8, P2RY2, FLNA, ITGAV, TLN1, GNB2L
Protein Size: 799

Molecular Weight: 88 kDa

Gene ID: 3693

NCBI Accession: NM_002213, NP_002204

UniProt: P18084

Pathways: Integrin Complex