Integrin beta 5 antibody (AA 690-770)

Catalog No. ABIN7215458

The Rabbit Polyclonal anti-Integrin beta 5 antibody is suitable to detect Integrin beta 5 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and ELISA.

Quick Overview for Integrin beta 5 antibody (AA 690-770) (ABIN7215458)

Target: Integrin beta 5 (ITGB5)

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Integrin beta 5 Antibody

Binding Specificity: AA 690-770

Purpose: Rabbit Anti-Integrin β5 Polyclonal Antibody

Specificity: Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Integrin beta5 at AA range: 690-770

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Integrin beta 5

Target: Integrin beta 5 (ITGB5)

Alternative Name: Integrin beta5

Background: ITGB5, Integrin beta-5ITGB5 is a Protein Coding gene. Integrin beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. Integrin beta-5 acts as a receptor for adenovirus type C. Diseases associated with ITGB5 include villous adenocarcinoma and localized scleroderma. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Degradation of the extracellular matrix. Gene Ontology (GO) annotations related to this gene include receptor activity and integrin binding. An important paralog of this gene is ITGB4.

Molecular Weight: 88kD

Gene ID: 3693

UniProt: P18084

Pathways: Integrin Complex