ITGB8 antibody (C-Term)

Catalog No. ABIN2782163

The Rabbit Polyclonal anti-ITGB8 antibody (ABIN2782163) specifically detects ITGB8 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit samples.

Quick Overview for ITGB8 antibody (C-Term) (ABIN2782163)

Target: ITGB8 (Integrin beta-8 (ITGB8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITGB8 Antibody

Binding Specificity: C-Term

Purpose: ITGB8 Antibody - C-terminal region

Sequence: CTDPRSIGRF CEHCPTCYTA CKENWNCMQC LHPHNLSQAI LDQCKTSCAL

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ITGB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ITGB8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45250-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITGB8

Target: ITGB8 (Integrin beta-8 (ITGB8))

Alternative Name: ITGB8

Background:

Background Information: ITGB8 is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation.This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.

Gene Name: Integrin, beta 8

Alternative Symbols: -

Protein Name: Integrin beta-8

Molecular Weight: 85 kDa

Gene ID: 3696

NCBI Accession: NP_002205

UniProt: P26012