Lamin B Receptor antibody (Middle Region)
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- Target See all Lamin B Receptor (LBR) Antibodies
- Lamin B Receptor (LBR)
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Lamin B Receptor antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Yeast: 77%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against LBR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LBR
- Top Product
- Discover our top product LBR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 615 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Lamin B Receptor (LBR)
- Alternative Name
- LBR (LBR Products)
- Synonyms
- CG17952 antibody, Dmel\\CG17952 antibody, dLBR antibody, sb:cb406 antibody, zgc:86649 antibody, wu:fb75h08 antibody, wu:fc47b04 antibody, wu:fd36b07 antibody, lbr-A antibody, Xp58 antibody, p58 gene antibody, LBR antibody, DHCR14B antibody, LMN2R antibody, PHA antibody, TDRD18 antibody, AI505894 antibody, ic antibody, Nbp60 antibody, lamin B receptor antibody, Lamin B receptor antibody, lamin B receptor S homeolog antibody, LBR antibody, lbr antibody, lbr.S antibody, Lbr antibody
- Background
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The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: DHCR14B, LMN2R, MGC9041, PHA
Protein Interaction Partner: UBC, EED, CLK3, HIPK4, LMNA, HNRNPR, EIF4A3, ILF2, HNRNPU, DHX15, DHX9, KCND3, PPP1CC, PPP1CB, PPP1CA, TCF3, ARRB2, SUMO2, HIST2H4A, HIST1H3A, tat, CBX5, SRPK1, FNBP4, AKAP8L, YWHAG, CBX3, LBR, PRM1, LMNB1, MECP2,
Protein Size: 615 - Molecular Weight
- 71 kDa
- Gene ID
- 3930
- NCBI Accession
- NM_002296, NP_002287
- UniProt
- Q14739
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