Synaptophysin antibody (N-Term)

Catalog No. ABIN2782216

The Rabbit Polyclonal anti-Synaptophysin antibody has been validated for WB and IHC. It is suitable to detect Synaptophysin in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) and Goat. There is 1 publication available.

Quick Overview for Synaptophysin antibody (N-Term) (ABIN2782216)

Target: Synaptophysin (SYP)

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Synaptophysin Antibody

Binding Specificity: N-Term

Sequence: MLLLADMDVV NQLVAGGQFR VVKEPLGFVK VLQWVFAIFA FATCGSYSGE

Predicted Reactivity: Cow: 100%, Dog: 92%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against SYP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Synaptophysin antibody (ABIN2782216)

Stenkamp-Strahm, Kappmeyer, Schmalz, Gericke, Balemba: "High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes." in: Cell and tissue research, Vol. 354, Issue 2, pp. 381-94, (2013) (PubMed).

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP

Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MRXSYP
Protein Interaction Partner: UBC, SRCIN1, SORBS3, Htt, AP1G1, SIAH2, SIAH1, VAMP2, GRB2, STX1A, EPOR,
Protein Size: 313

Molecular Weight: 34 kDa

Gene ID: 6855

NCBI Accession: NM_003179, NP_003170

UniProt: B2R7L6

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity