TGFB2 antibody (Middle Region)
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- Target See all TGFB2 Antibodies
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TGFB2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NLVKAEFRVF RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against TGFB2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TGFB2
- Top Product
- Discover our top product TGFB2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 414 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Alternative Name
- TGFB2 (TGFB2 Products)
- Synonyms
- LDS4 antibody, TGF-beta2 antibody, tgf-beta2 antibody, tgfb2-A antibody, BB105277 antibody, Tgf-beta2 antibody, Tgfb-2 antibody, TGF-beta 2 antibody, Tgfbr2T antibody, TGFB2 antibody, TGFbeta2 antibody, MGF antibody, TGF-B2 antibody, transforming growth factor beta 2 antibody, transforming growth factor beta 2 L homeolog antibody, transforming growth factor, beta 2 antibody, transforming growth factor, beta receptor 2 antibody, TGFB2 antibody, tgfb2.L antibody, Tgfb2 antibody, Tgfbr2 antibody, tgfb2 antibody
- Background
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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC116892, TGF-beta2
Protein Interaction Partner: CEBPA, UBC, VASN, PZP, LTBP3, TGFBR3, FMOD, VTN, TGFB3, TGFB2, TGFBR2, TGFBR1, TGFB1, ENG, CTGF, BMP2, APP, TGFBRAP1, DAXX, DCN,
Protein Size: 414 - Molecular Weight
- 46 kDa
- Gene ID
- 7042
- NCBI Accession
- NM_003238, NP_003229
- UniProt
- P61812
- Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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