ESRRG antibody (N-Term)

Catalog No. ABIN2782267

This Rabbit Polyclonal antibody specifically detects ESRRG in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for ESRRG antibody (N-Term) (ABIN2782267)

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ESRRG Antibody

Binding Specificity: N-Term

Purpose: ESRRG Antibody - N-terminal region

Sequence: DRHIDSSCSS FIKTEPSSPA SLTDSVNHHS PGGSSDASGS YSSTMNGHQN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ESRRG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ESRRG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099854

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ESRRG

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Alternative Name: ESRRG

Background:

Background Information: ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.

Gene Name: Estrogen-related receptor gamma

Alternative Symbols: ERR3, ERRg, NR3B3, ERRgamma, ERR-gamma

Protein Name: Estrogen-related receptor gamma

Molecular Weight: 51kDa

Gene ID: 2104

NCBI Accession: NP_001429

UniProt: P62508

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway