MBL2 antibody (Middle Region)

Catalog No. ABIN2782311

The Rabbit Polyclonal anti-MBL2 antibody (ABIN2782311) specifically detects MBL2 in WB. The antibody is reactive with Human, Rat, Cow, Goat, Sheep, Horse and Pig samples.

Quick Overview for MBL2 antibody (Middle Region) (ABIN2782311)

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reactivity: Human, Rat, Cow, Goat, Sheep, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MBL2 Antibody

Binding Specificity: Middle Region

Sequence: KEEAFLGITD EKTEGQFVDL TGNRLTYTNW NEGEPNNAGS DEDCVLLLKN

Predicted Reactivity: Cow: 77%, Goat: 77%, Horse: 92%, Human: 100%, Pig: 92%, Rat: 77%, Sheep: 77%

Characteristics: This is a rabbit polyclonal antibody against MBL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2

Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Alias Symbols: COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833, MBL2D, MBP-C
Protein Interaction Partner: MASP2, MAD2L1, MASP1, MBL2, PTPRC, KRT1, CD93, CALCR, CALR,
Protein Size: 248

Molecular Weight: 24 kDa

Gene ID: 4153

NCBI Accession: NM_000242, NP_000233

UniProt: Q66S64

Pathways: Complement System, Positive Regulation of Immune Effector Process