CPS1 antibody (N-Term)

Catalog No. ABIN2782318

The Rabbit Polyclonal anti-CPS1 antibody (ABIN2782318) specifically detects CPS1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit and Pig samples.

Quick Overview for CPS1 antibody (N-Term) (ABIN2782318)

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CPS1 Antibody

Binding Specificity: N-Term

Purpose: CPS1 Antibody - N-terminal region

Sequence: QWLQEEKVPA IYGVDTRMLT KIIRDKGTML GKIEFEGQPV DFVDPNKQNL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CPS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096150

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPS1

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Alternative Name: CPS1

Background:

Background Information: Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD, MIM 114010), which has been mapped to 2p21.[supplied by OMIM].

Gene Name: Carbamoyl-phosphate synthase 1, mitochondrial

Alternative Symbols: PHN, CPSASE1

Protein Name: Carbamoyl-phosphate synthase [ammonia], mitochondrial

Molecular Weight: 165kDa

Gene ID: 1373

NCBI Accession: NP_001866

UniProt: P31327

Pathways: Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process