CPS1 antibody (Middle Region)

Catalog No. ABIN2782319

This Rabbit Polyclonal antibody specifically detects CPS1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Guinea Pig, Cow, Rabbit, Horse and Saccharomyces cerevisiae.

Quick Overview for CPS1 antibody (Middle Region) (ABIN2782319)

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Cow, Rabbit, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CPS1 Antibody

Binding Specificity: Middle Region

Sequence: YPSVTNYLYV TYNGQEHDVN FDDHGMMVLG CGPYHIGSSV EFDWCAVSSI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against CPS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1500 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPS1

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Alternative Name: CPS1

Background: Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD, MIM 114010), which has been mapped to 2p21.[supplied by OMIM].
Alias Symbols: CPSASE1
Protein Interaction Partner: AGO2, ASB1, FBXO6, UBC, MRPS26, LRPPRC, TOMM70A, SEC22B, PCBP1, HSPA9, HSPA1A, FH, CPT1A, MYC, ELAVL1, SUMO2, RAD21, Csnk1e, Cdk1, RICTOR, YWHAQ, H2AFX, ARAF, RAF1,
Protein Size: 1500

Molecular Weight: 165 kDa

Gene ID: 1373

NCBI Accession: NM_001875, NP_001866

UniProt: P31327

Pathways: Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process