TDO2 antibody (N-Term)

Catalog No. ABIN2782334

The Rabbit Polyclonal anti-TDO2 antibody (ABIN2782334) specifically detects TDO2 in WB and IHC. The antibody is reactive with Human, Dog and Pig samples.

Quick Overview for TDO2 antibody (N-Term) (ABIN2782334)

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Reactivity: Human, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TDO2 Antibody

Binding Specificity: N-Term

Purpose: TDO2 Antibody - N-terminal region

Sequence: MSGCPFLGNN FGYTFKKLPV EGSEEDKSQT GVNRASKGGL IYGNYLHLEK

Predicted Reactivity: Dog: 79%, Human: 100%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against TDO2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TDO2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45716-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TDO2

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Alternative Name: TDO2

Background:

Background Information: Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.

Gene Name: Tryptophan 2,3-dioxygenase

Alternative Symbols: TO, TDO, TPH2, TRPO, HYPTRP

Protein Name: Tryptophan 2,3-dioxygenase

Molecular Weight: 48kDa

Gene ID: 6999

NCBI Accession: NP_005642

UniProt: P48775