TDO2 antibody (N-Term)

Catalog No. ABIN2782335

The Rabbit Polyclonal anti-TDO2 antibody has been validated for WB. It is suitable to detect TDO2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for TDO2 antibody (N-Term) (ABIN2782335)

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TDO2 Antibody

Binding Specificity: N-Term

Sequence: LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VVSRMHRVSV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against TDO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TDO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 406 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TDO2

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Alternative Name: TDO2

Background: Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
Alias Symbols: TDO, TPH2, TRPO, TO
Protein Interaction Partner: MOB3C, NGB, MOB1A, SDCBP2, ZFYVE26, DPM1, ASMTL, TDO2, SDCBP, PSMA1, EIF4E, NMNAT1, REL, MEOX2, PRMT6, KDM1A,
Protein Size: 406

Molecular Weight: 48 kDa

Gene ID: 6999

NCBI Accession: NM_005651, NP_005642

UniProt: P48775