UBASH3A antibody (Middle Region)

Catalog No. ABIN2782357

Product Details anti-UBASH3A Antibody

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Pig, Saccharomyces cerevisiae, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBASH3A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PCSLPRRSRG IKDFENDPPL SSCGIFQSRI AGDALLDSGI RISSVFASPA

Predicted Reactivity: Cow: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against UBASH3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBASH3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 661 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBASH3A

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Alternative Name: UBASH3A (UBASH3A Products)

Synonyms: UBASH3A antibody, CLIP4 antibody, STS-2 antibody, TULA antibody, TULA-1 antibody, 5830413C03Rik antibody, C330001M22 antibody, Sts-2 antibody, ubiquitin associated and SH3 domain containing A antibody, ubiquitin associated and SH3 domain containing, A antibody, UBASH3A antibody, Ubash3a antibody

Background: UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It also promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Alias Symbols: CLIP4, STS-2, TULA, TULA-1
Protein Interaction Partner: KRT40, SF3B4, SPRY2, DAZAP2, TP53BP2, REL, TRIM37, KCNE1, CBS, UBC, CRK, UBASH3B, PARK2, CBL, ABCE1, gag, AIFM1, EGFR, ALK, DNM1, UBB, UBE2L3,
Protein Size: 661

Molecular Weight: 74 kDa

Gene ID: 53347

NCBI Accession: NM_018961, NP_061834

UniProt: P57075