C21orf33 antibody (N-Term)

Catalog No. ABIN2782372

This anti-C21orf33 antibody is a Rabbit Polyclonal antibody detecting C21orf33 in WB and IHC. Suitable for Human, Rat, Mouse, Cow, Guinea Pig, Horse, Sheep and Zebrafish (Danio rerio).

Quick Overview for C21orf33 antibody (N-Term) (ABIN2782372)

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C21orf33 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-C21orf33 Antibody

Binding Specificity: N-Term

Sequence: SRGGAEVQIF APDVPQMHVI DHTKGQPSEG ESRNVLTESA RIARGKITDL

Predicted Reactivity: Cow: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against C21orf33. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf33

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 237 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C21orf33

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Alternative Name: C21orf33

Background: C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
Alias Symbols: D21S2048E, ES1, GT335, HES1, KNP-I, KNPH, KNPI
Protein Interaction Partner: UBC, SUMO1, NEDD8, APP, FRA10AC1,
Protein Size: 237

Molecular Weight: 21 kDa

Gene ID: 8209

NCBI Accession: NM_198155, NP_937798