C21orf2 antibody (C-Term)

Catalog No. ABIN2782374

Product Details anti-C21orf2 Antibody

Target: C21orf2 (Chromosome 21 Open Reading Frame 2 (C21orf2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C21orf2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DPLDSEEEAT SGAQDERGLK PPSRGQFPSL SARDASSSHR GRNVLTAILL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against C21orf2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C21orf2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C21orf2

Target: C21orf2 (Chromosome 21 Open Reading Frame 2 (C21orf2))

Alternative Name: C21orf2 (C21orf2 Products)

Background: Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
Alias Symbols: A2, YF5, YF5/A2
Protein Interaction Partner: GMCL1, ATOX1, UBC,
Protein Size: 215

Molecular Weight: 23 kDa

Gene ID: 755

NCBI Accession: NM_004928, NP_004919