PWP2 antibody (Middle Region)

Catalog No. ABIN2782375

Product Details anti-PWP2 Antibody

Target: PWP2 (PWP2H) (PWP2 (Periodic Tryptophan Protein) Homolog (PWP2H))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PWP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VQTGSIEGRH DLKTGRKELD KITAKHAAKG KAFTALCYSA DGHSILAGGM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PWP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PWP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 919 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PWP2 antibody (ABIN2782375)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for PWP2

Target: PWP2 (PWP2H) (PWP2 (Periodic Tryptophan Protein) Homolog (PWP2H))

Alternative Name: PWP2 (PWP2H Products)

Synonyms: 6530411D08Rik antibody, Pwp2h antibody, wdp103 antibody, EHOC-17 antibody, PWP2H antibody, UTP1 antibody, cb471 antibody, zgc:56063 antibody, PWP2 periodic tryptophan protein homolog (yeast) antibody, PWP2, small subunit processome component antibody, Pwp2 antibody, PWP2 antibody, pwp2h antibody

Background: PWP2 belongs to the WD repeat PWP2 family. It contains 14 WD repeats. The exact function of PWP2 is not known.
Alias Symbols: EHOC-17, PWP2H, UTP1
Protein Interaction Partner: CUL3, UBC, EED, RNF2, HECW2, TARDBP, MMS19, WDR36, IPO13, RRP9, CUL1, SIRT7, SUMO2, HDGF, USP36, TOM1L1,
Protein Size: 919

Molecular Weight: 102 kDa

Gene ID: 5822

NCBI Accession: NM_005049, NP_005040

UniProt: Q15269