CFAP298 (N-Term) antibody

Catalog No. ABIN2782393

There is 1 publication for this product available. The Rabbit Polyclonal anti-CFAP298 antibody is suitable to detect CFAP298 in samples from Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit and Rat. It has been validated for WB.

Quick Overview for CFAP298 (N-Term) antibody (ABIN2782393)

Target: CFAP298

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: CFAP298 Antibody - N-terminal region

Sequence: VLLHVKRGDE SQFLLQAPGS TELEELTVQV ARVYNGRLKV QRLCSEMEEL

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C21orf59. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf59

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45873-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details

Target: CFAP298

Background:

Background Information: This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Naturally occuring readthrough transcription occurs from this locus to the downstream t-complex 10 like (TCP10L) gene.

Gene Name: cilia and flagella associated protein 298

Alternative Symbols: Kur, FBB18, CILD26, C21orf48, C21orf59

Protein Name: cilia- and flagella-associated protein 298

Molecular Weight: 33kDa

Gene ID: 56683

NCBI Accession: NP_067077

UniProt: P57076