MRPS6 antibody (C-Term)

Catalog No. ABIN2782399

The Rabbit Polyclonal anti-MRPS6 antibody is suitable to detect MRPS6 in samples from Human. It has been validated for WB.

Quick Overview for MRPS6 antibody (C-Term) (ABIN2782399)

Target: MRPS6 (Mitochondrial Ribosomal Protein S6 (MRPS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPS6 Antibody

Binding Specificity: C-Term

Purpose: MRPS6 Antibody - C-terminal region

Sequence: ESMVEHLSRD IDVIRGNIVK HPLTQELKEC EGIVPVPLAE KLYSTKKRKK

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MRPS6. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MRPS6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45882-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS6

Target: MRPS6 (Mitochondrial Ribosomal Protein S6 (MRPS6))

Alternative Name: MRPS6

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q.

Gene Name: mitochondrial ribosomal protein S6

Alternative Symbols: S6mt, RPMS6, MRP-S6, C21orf101

Protein Name: 28S ribosomal protein S6, mitochondrial

Molecular Weight: 13 kDa

Gene ID: 64968

NCBI Accession: NP_115865

UniProt: P82932