SMC2 antibody (N-Term)

Catalog No. ABIN2782450

The Rabbit Polyclonal anti-SMC2 antibody (ABIN2782450) specifically detects SMC2 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio) and Saccharomyces cerevisiae samples.

Quick Overview for SMC2 antibody (N-Term) (ABIN2782450)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMC2 Antibody

Binding Specificity: N-Term

Purpose: SMC2 Antibody - N-terminal region

Sequence: ISNLSQVRAS NLQDLVYKNG QAGITKASVS ITFDNSDKKQ SPLGFEVHDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SMC2 . It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46043-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2

Background:

Background Information: SMC2 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Gene Name: Structural maintenance of chromosomes 2

Alternative Symbols: CAPE, CAP-E, SMC-2, SMC2L1

Protein Name: Structural maintenance of chromosomes protein 2

Molecular Weight: 32kDa

Gene ID: 10592

UniProt: O95347