BLK antibody (Middle Region)

Catalog No. ABIN2782461

The Rabbit Polyclonal anti-BLK antibody has been validated for WB. It is suitable to detect BLK in samples from Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for BLK antibody (Middle Region) (ABIN2782461)

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLK Antibody

Binding Specificity: Middle Region

Sequence: AVVTKEPIYI VTEYMARGCL LDFLKTDEGS RLSLPRLIDM SAQIAEGMAY

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BLK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BLK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BLK

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name: BLK

Background: BLK may function in a signal transduction pathway that is restricted to B-lymphoid cells.
Alias Symbols: MGC10442, MODY11
Protein Interaction Partner: CCDC33, EFS, STAT3, Mbp, HSP90AA1, ERBB2, EGFR, CBL, Nedd4, FCGR2B, CTR9, BCAS2, UBE3A, PLCG2, BCL2, BCR, CD79B, FCGR2A, CD79A, BCL2L1,
Protein Size: 505

Molecular Weight: 58 kDa

Gene ID: 640

NCBI Accession: NM_001715, NP_001706

UniProt: P51451

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling