PEX3 antibody (N-Term)

Catalog No. ABIN2782478

Cited in 1 publication. The Rabbit Polyclonal anti-PEX3 antibody (ABIN2782478) specifically detects PEX3 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for PEX3 antibody (N-Term) (ABIN2782478)

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PEX3 Antibody

Binding Specificity: N-Term

Purpose: PEX3 Antibody - N-terminal region

Sequence: KYGQKKIREI QEREAAEYIA QARRQYHFES NQRTCNMTVL SMLPTLREAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PEX3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PEX3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107890

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PEX3 antibody (ABIN2782478)

Libby, Bales, Orlicky, McManaman: "Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome." in: The Journal of biological chemistry, Vol. 291, Issue 46, pp. 24231-24246, (2016) (PubMed).

Target Details for PEX3

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Alternative Name: PEX3

Background:

Background Information: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, it is necessary for the import of peroxisomal membrane proteins in the peroxisomes.

Gene Name: Peroxisomal biogenesis factor 3

Alternative Symbols: TRG18, PBD10A, PBD10B

Protein Name: Peroxisomal biogenesis factor 3

Molecular Weight: 42kDa

Gene ID: 8504

NCBI Accession: NP_003621

UniProt: P56589