DFNA5 antibody (C-Term)

Catalog No. ABIN2782489

The Rabbit Polyclonal anti-DFNA5 antibody is suitable to detect DFNA5 in samples from Human, Rat, Cow, Dog and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for DFNA5 antibody (C-Term) (ABIN2782489)

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DFNA5 Antibody

Binding Specificity: C-Term

Sequence: AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR

Predicted Reactivity: Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 437 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DFNA5

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Alternative Name: DFNA5

Background: Hearing impairment is a heterogeneous condition with over 40 loci described. DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in its gene.
Alias Symbols: ICERE-1
Protein Interaction Partner: UBC, EGFR, PTN,
Protein Size: 437

Molecular Weight: 47 kDa

Gene ID: 1687

NCBI Accession: NM_001127453

UniProt: A4FVA8

Pathways: Sensory Perception of Sound