MAGEA6 antibody (Middle Region)

Catalog No. ABIN2782499

The Rabbit Polyclonal anti-MAGEA6 antibody (ABIN2782499) specifically detects MAGEA6 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Pig and Rabbit samples.

Quick Overview for MAGEA6 antibody (Middle Region) (ABIN2782499)

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGEA6 Antibody

Binding Specificity: Middle Region

Purpose: MAGEA6 Antibody - middle region

Sequence: APEEKIWEEL SVLEVFEGRE DSIFGDPKKL LTQYFVQENY LEYRQVPGSD

Predicted Reactivity: Dog: 83%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 83%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MAGEA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46125-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA6

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Alternative Name: MAGEA6

Background:

Background Information: MAGEA6 gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.

Gene Name: Melanoma antigen family A, 6

Alternative Symbols: CT1.6, MAGE6, MAGE3B, MAGE-3b

Protein Name: Melanoma-associated antigen 6

Molecular Weight: 35kDa

Gene ID: 4105

NCBI Accession: NP_005354

UniProt: P43360