NUP62 antibody (N-Term)

Catalog No. ABIN2782528

The Rabbit Polyclonal anti-NUP62 antibody has been validated for WB and IF. It is suitable to detect NUP62 in samples from Human, Mouse, Rat, Dog and Guinea Pig.

Quick Overview for NUP62 antibody (N-Term) (ABIN2782528)

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP62 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NUP62 Antibody

Binding Specificity: N-Term

Sequence: SGFNFGGTGA PTGGFTFGTA KTATTTPATG FSFSTSGTGG FNFGAPFQPA

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NUP62. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NUP62

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 522 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Alternative Name: NUP62

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP62 is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
Alias Symbols: DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, SNDI, p62
Protein Interaction Partner: CEP57L1, CCDC150, SSC5D, KANSL1, CCDC153, TXLNA, AGR3, C1orf216, IKBIP, HAUS1, KLHL32, IFT20, MYO15B, CENPU, CCDC121, CCDC146, THAP1, CRCT1, CCHCR1, KRT20, NUP54, PHF21A, CCDC53, BLOC1S6, ISCU, XPO6, OIP5, NXF1, SNAPC5, NUTF2, ABI2, NUPL1, ADAM15, UBC, SM
Protein Size: 522

Molecular Weight: 53 kDa

Gene ID: 23636

NCBI Accession: NM_012346, NP_036478

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interactome