B-Cell Linker antibody (Middle Region)
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- Target See all B-Cell Linker (BLNK) Antibodies
- B-Cell Linker (BLNK)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This B-Cell Linker antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QYALGRKKNG EEYFGSVAEI IRNHQHSPLV LIDSQNNTKD STRLKYAVKV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BLNK. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human BLNK
- Top Product
- Discover our top product BLNK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 456 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- B-Cell Linker (BLNK)
- Alternative Name
- BLNK (BLNK Products)
- Synonyms
- BLNK antibody, blnk antibody, MGC147045 antibody, BASH antibody, Bca antibody, Ly-57 antibody, Ly57 antibody, Lyw-57 antibody, SLP-65 antibody, AGM4 antibody, BLNK-S antibody, LY57 antibody, SLP65 antibody, bca antibody, B-cell linker antibody, B cell linker antibody, BLNK antibody, blnk antibody, Blnk antibody
- Background
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This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological function
Alias Symbols: BASH, BLNK-s, Ly57, MGC111051, SLP-65, SLP65, bca, AGM4, LY57, BLNK-S
Protein Interaction Partner: ERBB2, BTK, GRAP2, SYK, PLCG1, CBL, AIFM1, NCK2, TLN1, MAP2K4, PPP2R2C, PLCG2, MYBPC3, LYN, HSPA4, GRB2, CD79A, CAPZB, CAPZA2, CAPZA1, CLEC17A, WDR81, DOK3, SH3KBP1, CD2AP, HSPH1, VAV3, CMTM3, CBLB, CRKL, MAP4K1, LCP2, NCK1, ITK, PTPN6, VAV1, CD72,
Protein Size: 456 - Molecular Weight
- 50 kDa
- Gene ID
- 29760
- NCBI Accession
- NM_013314, NP_037446
- UniProt
- Q8WV28
- Pathways
- BCR Signaling
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