Septin 6 antibody (Middle Region)

Catalog No. ABIN2782543

This Rabbit Polyclonal antibody specifically detects Septin 6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for Septin 6 antibody (Middle Region) (ABIN2782543)

Target: Septin 6 (SEPT6)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Septin 6 Antibody

Binding Specificity: Middle Region

Purpose: SEPT6 Antibody - middle region

Sequence: CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SEPT6(septin 6) . It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEPT6(septin 6)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8117283

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Septin 6

Target: Septin 6 (SEPT6)

Alternative Name: SEPT6

Background:

Background Information: SEPT6 is a member of the septin family of GTPases. Members of this family are required for cytokinesis.This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Gene Name: Septin 6

Alternative Symbols: SEP2, SEPT2, SEPT6

Protein Name: Septin-6

Molecular Weight: 50kDa

Gene ID: 23157

NCBI Accession: NP_055944

UniProt: Q14141