BOP1 antibody (N-Term)

Catalog No. ABIN2782546

Cited in 1 publication. The Rabbit Polyclonal anti-BOP1 antibody (ABIN2782546) specifically detects BOP1 in WB. The antibody is reactive with Human, Rat, Horse, Pig, Dog, Cow, Guinea Pig, Rabbit and Saccharomyces cerevisiae samples.

Quick Overview for BOP1 antibody (N-Term) (ABIN2782546)

Target: BOP1 (Block of Proliferation 1 (BOP1))

Reactivity: Human, Rat, Horse, Pig, Dog, Cow, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BOP1 Antibody

Binding Specificity: N-Term

Purpose: BOP1 Antibody - N-terminal region

Sequence: PLLCTSPLSH STGSDSGVSD SEESVFSGLE DSGSDSSEDD DEGDEEGEDG

Predicted Reactivity: Cow: 77%, Dog: 77%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Pig: 91%, Rabbit: 82%, Rat: 83%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against BOP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BOP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46224-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BOP1 antibody (ABIN2782546)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for BOP1

Target: BOP1 (Block of Proliferation 1 (BOP1))

Alternative Name: BOP1

Background:

Background Information: BOP1 is the component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Gene Name: Block of proliferation 1

Alternative Symbols: KIAA0124

Protein Name: Ribosome biogenesis protein BOP1

Molecular Weight: 83kDa

Gene ID: 23246

NCBI Accession: NP_056016

UniProt: Q14137