GINS2 antibody (C-Term)

Catalog No. ABIN2782554

The Rabbit Polyclonal anti-GINS2 antibody (ABIN2782554) specifically detects GINS2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog and Horse samples.

Quick Overview for GINS2 antibody (C-Term) (ABIN2782554)

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GINS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GINS2 Antibody

Binding Specificity: C-Term

Purpose: GINS2 Antibody - C-terminal region

Sequence: VRQQEAHAKL DNLTLMEINT SGTFLTQALN HMYKLRTNLQ PLESTQSQDF

Predicted Reactivity: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GINS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GINS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101478

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GINS2

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Alternative Name: GINS2

Background:

Background Information: The yeast heterotetrameric GINS complex is made up of Sld5, Psf1, Psf2, and Psf3. The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts.The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1 (GINS1, MIM 610608), Psf2, and Psf3 (GINS3, MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM].

Gene Name: GINS complex subunit 2 (Psf2 homolog)

Alternative Symbols: PSF2, Pfs2, HSPC037

Protein Name: DNA replication complex GINS protein PSF2

Molecular Weight: 21kDa

Gene ID: 51659

NCBI Accession: NP_057179

UniProt: Q9Y248

Pathways: DNA Replication, Synthesis of DNA