ASF1B antibody (Middle Region)

Catalog No. ABIN2782568

This anti-ASF1B antibody is a Rabbit Polyclonal antibody detecting ASF1B in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for ASF1B antibody (Middle Region) (ABIN2782568)

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASF1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASF1B Antibody

Binding Specificity: Middle Region

Sequence: YHGQEFIRVG YYVNNEYLNP ELRENPPMKP DFSQLQRNIL ASNPRVTRFH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ASF1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASF1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 202 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASF1B

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Alternative Name: ASF1B

Background: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.
Alias Symbols: CIA-II, FLJ10604
Protein Interaction Partner: UBC, HIST3H3, H3F3A, MMS22L, TONSL, MCM6, HIST4H4, HIST1H3A, KHSRP, IDH1, CDAN1, IPO4, ASF1A, HIST1H3C, TLK2, HIST1H3E, MCM2, HAT1, RBBP7, CHAF1B, HIRA, UL30, UL52, HCFC1, C15orf41, TLK1, HIST1H4F, HIST1H3B, CHAF1A, H3F3B, TAF1, MRPS7, UBXN1, DOK2, HIST1H
Protein Size: 202

Molecular Weight: 22 kDa

Gene ID: 55723

NCBI Accession: NM_018154, NP_060624

UniProt: Q9NVP2

Pathways: Regulation of Cell Size