PSAT1 antibody (N-Term)

Catalog No. ABIN2782576

This Rabbit Polyclonal antibody specifically detects PSAT1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been mentioned in 2+ publications

Quick Overview for PSAT1 antibody (N-Term) (ABIN2782576)

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PSAT1 Antibody

Binding Specificity: N-Term

Purpose: PSAT1 Antibody - N-terminal region

Sequence: ADYVVTGAWS AKAAEEAKKF GTINIVHPKL GSYTKIPDPS TWNLNPDASY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PSAT1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSAT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108239

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSAT1 antibody (ABIN2782576)

Yoon, Kim, Seo, Park, Kim, Park, Choi, Jeong, Jun, Yoon, Kang: "Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer." in: Oncology, Vol. 89, Issue 6, pp. 351-9, (2015) (PubMed).

Yang, Wu, Cai, He, Yuan, Zhu, Li, Li, Guan: "PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells." in: International journal of cancer, Vol. 136, Issue 4, pp. E39-50, (2014) (PubMed).

Target Details for PSAT1

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Alternative Name: PSAT1

Background:

Background Information: PSAT1 is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila.The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene Name: Phosphoserine aminotransferase 1

Alternative Symbols: PSA, EPIP, NLS2, PSAT, PSATD

Protein Name: Phosphoserine aminotransferase

Molecular Weight: 40kDa

Gene ID: 29968

NCBI Accession: NP_478059

UniProt: Q9Y617

Pathways: Warburg Effect