PPCDC antibody (N-Term)

Catalog No. ABIN2782577

The Rabbit Polyclonal anti-PPCDC antibody is suitable to detect PPCDC in samples from Human, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit and Rat. It has been validated for WB.

Quick Overview for PPCDC antibody (N-Term) (ABIN2782577)

Target: PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))

Reactivity: Human, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPCDC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPCDC Antibody

Binding Specificity: N-Term

Purpose: PPCDC Antibody - N-terminal region

Sequence: VTTERAKHFY SPQDIPVTLY SDADEWEIWK SRSDPVLHID LRRWADLLLV

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PPCDC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPCDC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPCDC

Target: PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))

Alternative Name: PPCDC

Background:

Background Information: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC, one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine.

Gene Name: Phosphopantothenoylcysteine decarboxylase

Alternative Symbols: coaC, MDS018, PPC-DC

Protein Name: Phosphopantothenoylcysteine decarboxylase

Molecular Weight: 22kDa

Gene ID: 60490

NCBI Accession: NP_068595

UniProt: Q96CD2

Pathways: Ribonucleoside Biosynthetic Process