Adam23 antibody (N-Term)

Catalog No. ABIN2782599

The Rabbit Polyclonal anti-Adam23 antibody is suitable to detect Adam23 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Pig. It has been validated for WB.

Quick Overview for Adam23 antibody (N-Term) (ABIN2782599)

Target: Adam23 (ADAM Metallopeptidase Domain 23 (Adam23))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adam23 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adam23 Antibody

Binding Specificity: N-Term

Purpose: ADAM23 Antibody - N-terminal region

Sequence: SAPHWNETAE KNLGVLADED NTLQQNSSSN ISYSNAMQKE ITLPSRLIYY

Predicted Reactivity: Cow: 93%, Dog: 92%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against ADAM23. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ADAM23

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46365-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adam23

Target: Adam23 (ADAM Metallopeptidase Domain 23 (Adam23))

Alternative Name: ADAM23

Background:

Background Information: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers.

Gene Name: ADAM metallopeptidase domain 23

Alternative Symbols: MDC3, MDC-3

Protein Name: Disintegrin and metalloproteinase domain-containing protein 23

Molecular Weight: 91kDa

Gene ID: 8745

NCBI Accession: NP_003803

UniProt: O75077