FcRn antibody (N-Term)

Catalog No. ABIN2782616

The Rabbit Polyclonal anti-FcRn antibody is suitable to detect FcRn in samples from Human, Mouse, Cow, Dog, Guinea Pig, Horse and Sheep. It has been validated for WB and IHC.

Quick Overview for FcRn antibody (N-Term) (ABIN2782616)

Target: FcRn (neonatal Fc Receptor (FcRn))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FcRn antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FcRn Antibody

Binding Specificity: N-Term

Sequence: GWLGPQQYLS YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against FCGRT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FCGRT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FcRn

Target: FcRn (neonatal Fc Receptor (FcRn))

Alternative Name: FCGRT

Background: FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.
Alias Symbols: FCRN, alpha-chain
Protein Interaction Partner: ATG16L1, FCGRT, CA6, B2M, ALB,
Protein Size: 365

Molecular Weight: 40 kDa

Gene ID: 2217

NCBI Accession: NM_004107, NP_004098

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process