Cadherin 7 antibody (N-Term)

Catalog No. ABIN2782629

This Rabbit Polyclonal antibody specifically detects Cadherin 7 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Horse, Rabbit and Guinea Pig.

Quick Overview for Cadherin 7 antibody (N-Term) (ABIN2782629)

Target: Cadherin 7 (CDH7)

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cadherin 7 Antibody

Binding Specificity: N-Term

Purpose: CDH7 Antibody - N-terminal region

Sequence: PKFLDGPYTA GVPEMSPVGT SVVQVTATDA DDPTYGNSAR VVYSILQGQP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDH7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDH7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46435-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cadherin 7

Target: Cadherin 7 (CDH7)

Alternative Name: CDH7

Background:

Background Information: CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

Gene Name: Cadherin 7, type 2

Alternative Symbols: CDH7L1

Protein Name: Cadherin-7

Molecular Weight: 82kDa

Gene ID: 1005

NCBI Accession: NP_004352

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization