Tspan-8 antibody (Middle Region)

Catalog No. ABIN2782647

The Rabbit Polyclonal anti-Tspan-8 antibody (ABIN2782647) specifically detects Tspan-8 in WB. The antibody is reactive with Human, Mouse and Guinea Pig samples.

Quick Overview for Tspan-8 antibody (Middle Region) (ABIN2782647)

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Reactivity: Human, Mouse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tspan-8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tspan-8 Antibody

Binding Specificity: Middle Region

Purpose: TSPAN8 Antibody - middle region

Sequence: VFKSKSDRIV NETLYENTKL LSATGESEKQ FQEAIIVFQE EFKCCGLVNG

Predicted Reactivity: Guinea Pig: 75%, Human: 100%, Mouse: 82%

Characteristics: This is a rabbit polyclonal antibody against TSPAN8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSPAN8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46477-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tspan-8

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Alternative Name: TSPAN8

Background:

Background Information: TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN8 is a cell surface glycoprotein that is known to complex with integrins. TSPAN8 is expressed in different carcinomas.The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Gene Name: Tetraspanin 8

Alternative Symbols: CO-029, TM4SF3

Protein Name: Tetraspanin-8

Molecular Weight: 26kDa

Gene ID: 7103

NCBI Accession: NP_004607

UniProt: P19075