NDST3 antibody (N-Term)

Catalog No. ABIN2782656

The Rabbit Polyclonal anti-NDST3 antibody (ABIN2782656) specifically detects NDST3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for NDST3 antibody (N-Term) (ABIN2782656)

Target: NDST3 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 3 (NDST3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDST3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDST3 Antibody

Binding Specificity: N-Term

Purpose: NDST3 Antibody - N-terminal region

Sequence: PGTDWTVFQI NHSAYQPVIF AKVKTPENLS PSISKGAFYA TIIHDLGLHD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NDST3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NDST3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46503-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDST3

Target: NDST3 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 3 (NDST3))

Alternative Name: NDST3

Background:

Background Information: NDST3 is a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. NDST3 is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.

Gene Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

Alternative Symbols: HSST3

Protein Name: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

Molecular Weight: 101kDa

Gene ID: 9348

NCBI Accession: NP_004775

UniProt: O95803

Pathways: Glycosaminoglycan Metabolic Process