SSPN antibody (Middle Region)

Catalog No. ABIN2782663

This Rabbit Polyclonal antibody specifically detects SSPN in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Guinea Pig and Horse.

Quick Overview for SSPN antibody (Middle Region) (ABIN2782663)

Target: SSPN (Sarcospan (Kras Oncogene-Associated Gene) (SSPN))

Reactivity: Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSPN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SSPN Antibody

Binding Specificity: Middle Region

Purpose: SSPN Antibody - middle region

Sequence: AHHYSQLTQF TCETTLDSCQ CKLPSSEPLS RTFVYRDVTD CTSVTGTFKL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SSPN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SSPN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46567-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSPN

Target: SSPN (Sarcospan (Kras Oncogene-Associated Gene) (SSPN))

Alternative Name: SSPN

Background:

Background Information: SSPN is a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells.SSPN gene is expressed in a variety of tissues with highest levels in muscle, where alternative splice variants have been observed. In certain tumors KRAS2, SSPN, and ITPR2 are coamplified. The function of this gene is unknown. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Sarcospan

Alternative Symbols: KRAG, NSPN, SPN1, SPN2, DAGA5

Protein Name: Sarcospan

Molecular Weight: 26kDa

Gene ID: 8082

NCBI Accession: NP_005077

UniProt: Q14714