TSPAN32 antibody (Middle Region)

Catalog No. ABIN2782686

This Rabbit Polyclonal antibody specifically detects TSPAN32 in WB. It exhibits reactivity toward Human and Horse.

Quick Overview for TSPAN32 antibody (Middle Region) (ABIN2782686)

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN32 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSPAN32 Antibody

Binding Specificity: Middle Region

Sequence: EDCLQGIRSF LRTHQQVASS LTSIGLALTV SALLFSSFLW FAIRCGCSLD

Predicted Reactivity: Horse: 100%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TSPAN32. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSPAN32

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Alternative Name: TSPAN32

Background: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. This gene is described as a member of the tetraspanin superfamily.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes, however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4 (TSSC4), escapes imprinting. This gene may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. This gene is described as a member of the tetraspanin superfamily. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Alias Symbols: MGC22455, PHEMX, PHMX, TSSC6, ART1
Protein Size: 290

Molecular Weight: 31 kDa

Gene ID: 10077

NCBI Accession: NM_005705, NP_005696