MMP16 antibody (N-Term)

Catalog No. ABIN2782697

The Rabbit Polyclonal anti-MMP16 antibody (ABIN2782697) specifically detects MMP16 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Rabbit, Horse and Guinea Pig samples.

Quick Overview for MMP16 antibody (N-Term) (ABIN2782697)

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP16 Antibody

Binding Specificity: N-Term

Purpose: MMP16 Antibody - N-terminal region

Sequence: ALAAMQQFYG INMTGKVDRN TIDWMKKPRC GVPDQTRGSS KFHIRRKRYA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP16

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46674-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP16

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Alternative Name: MMP16

Background:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another soluble form of the protein. Both forms of the protein activate MMP2 by cleavage.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Gene Name: Matrix metallopeptidase 16 (membrane-inserted)

Alternative Symbols: MMP-X2, C8orf57, MT-MMP2, MT-MMP3, MT3-MMP

Protein Name: Matrix metalloproteinase-16

Molecular Weight: 56kDa

Gene ID: 4325

NCBI Accession: NP_005932

UniProt: P51512