HS3ST3B1 antibody (N-Term)

Catalog No. ABIN2782700

The Rabbit Polyclonal anti-HS3ST3B1 antibody is suitable to detect HS3ST3B1 in samples from Human, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit and Rat. It has been validated for WB.

Quick Overview for HS3ST3B1 antibody (N-Term) (ABIN2782700)

Target: HS3ST3B1 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 3B1 (HS3ST3B1))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS3ST3B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HS3ST3B1 Antibody

Binding Specificity: N-Term

Purpose: HS3ST3B1 Antibody - N-terminal region

Sequence: AMLCVWLYMF LYSCAGSCAA APGLLLLGSG SRAAHDPPAL ATAPDGTPPR

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 87%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HS3ST3B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HS3ST3B1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46685-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HS3ST3B1

Target: HS3ST3B1 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 3B1 (HS3ST3B1))

Alternative Name: HS3ST3B1

Background:

Background Information: HS3ST3B1 is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.

Gene Name: Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1

Alternative Symbols: 3OST3B1, 3-OST-3B, h3-OST-3B

Protein Name: Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

Molecular Weight: 43kDa

Gene ID: 9953

NCBI Accession: NP_006032

UniProt: Q9Y662

Pathways: Glycosaminoglycan Metabolic Process