ST3GAL4 antibody (Middle Region)

Catalog No. ABIN2782703

The Rabbit Polyclonal anti-ST3GAL4 antibody (ABIN2782703) specifically detects ST3GAL4 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit and Sheep samples.

Quick Overview for ST3GAL4 antibody (Middle Region) (ABIN2782703)

Target: ST3GAL4 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 4 (ST3GAL4))

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ST3GAL4 Antibody

Binding Specificity: Middle Region

Sequence: IKQKPTTGLL AITLALHLCD LVHIAGFGYP DAYNKKQTIH YYEQITLKSM

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ST3GAL4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ST3GAL4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 329 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ST3GAL4

Target: ST3GAL4 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 4 (ST3GAL4))

Alternative Name: ST3GAL4

Background: It may catalyze the formation of the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc-sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.Synthesis of alpha-2,3-linked sialic acid to Gal(beta-1,3)GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2,3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a single gene encodes the beta-galactoside alpha-2,6-sialyltransferase (EC 2.4.99.1), ST6GAL1 (MIM 109675) (Chang et al., 1995 [PubMed 7655169]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, ST3Gal IV, ST3GalIV, STZ
Protein Interaction Partner: UBC, ARHGDIA, CD8B,
Protein Size: 329

Molecular Weight: 37 kDa

Gene ID: 6484

NCBI Accession: NM_006278, NP_006269

UniProt: Q6IBE6

Pathways: Glycosaminoglycan Metabolic Process