FKBP8 antibody (N-Term)

Catalog No. ABIN2782772

This Rabbit Polyclonal antibody specifically detects FKBP8 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow and Goat.

Quick Overview for FKBP8 antibody (N-Term) (ABIN2782772)

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FKBP8 Antibody

Binding Specificity: N-Term

Sequence: GPPGSSRPVK GQVVTVHLQT SLENGTRVQE EPELVFTLGD CDVIQALDLS

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FKBP8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 413 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP8

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Alternative Name: FKBP8

Background: FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, it does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FKBP38, FKBPr38
Protein Interaction Partner: UBC, RHEB, RICTOR, MLST8, RPTOR, MTOR, PDCL, CACYBP, HSPBP1, SUGT1, PTGES3, HCVgp1, CDK20, ADRB2, CLN3, ARHGEF5, HSP90AA1, CAMK2A, BNIPL, CALM1, BCL2, FKBP8, KCNH2, MRPL11, TOMM22, MRPL15, NNT, PGRMC1, YME1L1, UQCRFS1, UQCRC2, UQCRC1, SURF1, SSR1, DHODH,
Protein Size: 413

Molecular Weight: 45 kDa

Gene ID: 23770

NCBI Accession: NM_012181, NP_036313

UniProt: Q14318

Pathways: Autophagy