TRAM2 antibody (N-Term)

Catalog No. ABIN2782778

The Rabbit Polyclonal anti-TRAM2 antibody is suitable to detect TRAM2 in samples from Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow and Pig. It has been validated for WB.

Quick Overview for TRAM2 antibody (N-Term) (ABIN2782778)

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRAM2 Antibody

Binding Specificity: N-Term

Purpose: TRAM2 Antibody - N-terminal region

Sequence: MFEVTAKTAF LFILPQYNIS VPTADSETVH YHYGPKDLVT ILFYIFITII

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TRAM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRAM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46879-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRAM2

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Alternative Name: TRAM2

Background:

Background Information: TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM].

Gene Name: Translocation associated membrane protein 2

Alternative Symbols: KIAA0057

Protein Name: Translocating chain-associated membrane protein 2

Molecular Weight: 43kDa

Gene ID: 9697

NCBI Accession: NP_036420

UniProt: Q15035