TRAM2 antibody (C-Term)

Catalog No. ABIN2782779

This Rabbit Polyclonal antibody specifically detects TRAM2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow and Zebrafish (Danio rerio).

Quick Overview for TRAM2 antibody (C-Term) (ABIN2782779)

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRAM2 Antibody

Binding Specificity: C-Term

Purpose: Tram2 Antibody - C-terminal region

Sequence: YWKEQSAKRR VSAVPRPPAK LLKREPGYHE NGVVKAENGT SSRTKKLKSP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Tram2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Tram2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46880-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRAM2

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Alternative Name: Tram2

Background:

Background Information: Tram2 is necessary for collagen type I synthesis. It may couple the activity of the ER Ca2+  pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+  concentration at the site of collagen synthesis, and a high Ca2+  concentration may be necessary for the function of molecular chaperones involved in collagen folding.

Gene Name: translocation associated membrane protein 2

Alternative Symbols: C330003D03Rik

Protein Name: Translocating chain-associated membrane protein 2

Molecular Weight: 40kDa

Gene ID: 170829

NCBI Accession: NP_803128

UniProt: Q924Z5